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Water in the Active Site of Ketosteroid Isomerase

Classical molecular dynamics simulations were utilized to investigate the structural and dynamical properties of water in the active site of ketosteroid isomerase (KSI) to provide insight into the role of these water molecules in the enzyme-catalyzed reaction. This reaction is thought to proceed via...

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Bibliografiske detaljer
Main Authors: Hanoian, Philip, Hammes-Schiffer, Sharon
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149774/
https://ncbi.nlm.nih.gov/pubmed/21710970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi200703y
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