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Water in the Active Site of Ketosteroid Isomerase

Classical molecular dynamics simulations were utilized to investigate the structural and dynamical properties of water in the active site of ketosteroid isomerase (KSI) to provide insight into the role of these water molecules in the enzyme-catalyzed reaction. This reaction is thought to proceed via...

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Bibliografski detalji
Glavni autori: Hanoian, Philip, Hammes-Schiffer, Sharon
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149774/
https://ncbi.nlm.nih.gov/pubmed/21710970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi200703y
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