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Targeting human inducible regulatory T cells (Tr1) in patients with cancer: blocking of adenosine-prostaglandin E(2) cooperation

INTRODUCTION: Emerging data suggest that human inducible Treg (Tr1) produce adenosine and prostaglandin E(2) and that these factors cooperate in mediating immune suppression. AREAS COVERED: Human Tr1 present in human tumors or blood of cancer patients express ectonucleotidases, CD39 and/or CD73, hyd...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Mandapathil, M., Whiteside, T.L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149765/
https://ncbi.nlm.nih.gov/pubmed/21702720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/14712598.2011.581225
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