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Targeting human inducible regulatory T cells (Tr1) in patients with cancer: blocking of adenosine-prostaglandin E(2) cooperation
INTRODUCTION: Emerging data suggest that human inducible Treg (Tr1) produce adenosine and prostaglandin E(2) and that these factors cooperate in mediating immune suppression. AREAS COVERED: Human Tr1 present in human tumors or blood of cancer patients express ectonucleotidases, CD39 and/or CD73, hyd...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3149765/ https://ncbi.nlm.nih.gov/pubmed/21702720 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/14712598.2011.581225 |
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