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The role of Bcl-2 and its pro-survival relatives in tumourigenesis and cancer therapy
Tumour development requires a combination of defects that allow nascent neoplastic cells to become self-sufficient for cell proliferation and insensitive to signals that normally restrain cell growth. Among the latter, evasion of programmed cell death (apoptosis) has proven to be critical for the de...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3149740/ https://ncbi.nlm.nih.gov/pubmed/21415859 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2011.17 |
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