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Sequential and opposing alterations of 5-HT(1A) receptor function during withdrawal from chronic morphine

Addiction is a brain chronic relapsing disorder associated with emotional distress. The serotonergic system and especially the 5-HT(1A) receptor crucially regulate emotional behaviors both in humans and rodents. Using [(35)S]GTPγS autoradiography in mice, we show that 5-HT(1A) receptor function is e...

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Detalhes bibliográficos
Main Authors: Lutz, Pierre-Eric, Pradhan, Amynah A., Goeldner, Celia, Kieffer, Brigitte L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149735/
https://ncbi.nlm.nih.gov/pubmed/21402471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.euroneuro.2011.02.002
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