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Impaired emotional-like behavior and serotonergic function during protracted abstinence from chronic morphine

BACKGROUND: Opiate abuse is a chronic relapsing disorder and maintaining prolonged abstinence remains a major challenge. Protracted abstinence is characterized by lowered mood and clinical studies show elevated co-morbidity between addiction and depressive disorders. At present, their relationship r...

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Bibliografische gegevens
Hoofdauteurs: Goeldner, Celia, Lutz, Pierre-Eric, Darcq, Emmanuel, Halter, Thomas, Clesse, Daniel, Ouagazzal, Abdel-Mouttalib, Kieffer, Brigitte L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3014999/
https://ncbi.nlm.nih.gov/pubmed/20947067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2010.08.021
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