Lanean...

The unfolded protein response and proteostasis in Alzheimer disease: Preferential activation of autophagy by endoplasmic reticulum stress

Protein folding stress in the endoplasmic reticulum (ER) may lead to activation of the unfolded protein response (UPR), aimed to restore proteostasis in the ER. Previously, we demonstrated that UPR activation is an early event in Alzheimer disease (AD) brain. In our recent work we investigated wheth...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Scheper, Wiep, Nijholt, Diana AT, Hoozemans, Jeroen JM
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Landes Bioscience 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149694/
https://ncbi.nlm.nih.gov/pubmed/21494086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.7.8.15761
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!