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BBC3 (PUMA) regulates developmental apoptosis but not axonal injury induced death in the retina
BACKGROUND: Naturally occurring apoptosis is a developmental process that shapes the retina by eliminating overproduced neurons. In the absence of the proapoptotic Bcl-2 family member BAX, developmental apoptosis in the retina is disrupted and extra neurons survive. It is unknown how BAX is activate...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BioMed Central
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3149592/ https://ncbi.nlm.nih.gov/pubmed/21762490 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-6-50 |
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