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Transport Activity of the High-affinity Monocarboxylate Transporter MCT2 Is Enhanced by Extracellular Carbonic Anhydrase IV but Not by Intracellular Carbonic Anhydrase II

The ubiquitous enzyme carbonic anhydrase isoform II (CAII) has been shown to enhance transport activity of the proton-coupled monocarboxylate transporters MCT1 and MCT4 in a non-catalytic manner. In this study, we investigated the role of cytosolic CAII and of the extracellular, membrane-bound CA is...

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書誌詳細
主要な著者: Klier, Michael, Schüler, Christina, Halestrap, Andrew P., Sly, William S., Deitmer, Joachim W., Becker, Holger M.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149368/
https://ncbi.nlm.nih.gov/pubmed/21680735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.255331
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