Constitutive Regulatory Activity of an Evolutionarily Excluded Riboswitch Variant

The exquisite specificity of the adenine-responsive riboswitch toward its cognate metabolite has been shown to arise from the formation of a Watson-Crick interaction between the adenine ligand and residue U65. A recent crystal structure of a U65C adenine aptamer variant has provided a rationale for...

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Tallennettuna:
Bibliografiset tiedot
Päätekijät: Tremblay, Renaud, Lemay, Jean-François, Blouin, Simon, Mulhbacher, Jérôme, Bonneau, Éric, Legault, Pascale, Dupont, Paul, Penedo, J. Carlos, Lafontaine, Daniel A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2011
Aiheet:
Gene Regulation
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149334/
https://ncbi.nlm.nih.gov/pubmed/21676871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.229047
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