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Constitutive Regulatory Activity of an Evolutionarily Excluded Riboswitch Variant
The exquisite specificity of the adenine-responsive riboswitch toward its cognate metabolite has been shown to arise from the formation of a Watson-Crick interaction between the adenine ligand and residue U65. A recent crystal structure of a U65C adenine aptamer variant has provided a rationale for...
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| Autors principals: | , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3149334/ https://ncbi.nlm.nih.gov/pubmed/21676871 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.229047 |
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