Cytokine-like 1 Knock-out Mice (Cytl1(−/−)) Show Normal Cartilage and Bone Development but Exhibit Augmented Osteoarthritic Cartilage Destruction

We have shown that cytokine-like 1 (Cytl1) is a novel autocrine regulatory factor that regulates chondrogenesis of mouse mesenchymal cells (Kim, J. S., Ryoo, Z. Y., and Chun, J. S. (2007) J. Biol. Chem. 282, 29359–29367). In this previous work, we found that Cytl1 expression was very low in mesenchy...

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Bibliographische Detailangaben
Hauptverfasser: Jeon, Jimin, Oh, Hwanhee, Lee, Gyusuk, Ryu, Je-Hwang, Rhee, Jinseol, Kim, Jin-Hong, Chung, Kyung-Hwun, Song, Woo-Keun, Chun, Churl-Hong, Chun, Jang-Soo
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2011
Schlagworte:
Molecular Bases of Disease
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149314/
https://ncbi.nlm.nih.gov/pubmed/21652695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.218065
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