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Cytokine-like 1 Knock-out Mice (Cytl1(−/−)) Show Normal Cartilage and Bone Development but Exhibit Augmented Osteoarthritic Cartilage Destruction

We have shown that cytokine-like 1 (Cytl1) is a novel autocrine regulatory factor that regulates chondrogenesis of mouse mesenchymal cells (Kim, J. S., Ryoo, Z. Y., and Chun, J. S. (2007) J. Biol. Chem. 282, 29359–29367). In this previous work, we found that Cytl1 expression was very low in mesenchy...

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Detalhes bibliográficos
Main Authors: Jeon, Jimin, Oh, Hwanhee, Lee, Gyusuk, Ryu, Je-Hwang, Rhee, Jinseol, Kim, Jin-Hong, Chung, Kyung-Hwun, Song, Woo-Keun, Chun, Churl-Hong, Chun, Jang-Soo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149314/
https://ncbi.nlm.nih.gov/pubmed/21652695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.218065
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