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Modulation of Contact Order Effects in the Two-State Folding of Stefins A and B

It is well established that contact order and folding rates are correlated for small proteins. The folding rates of stefins A and B differ by nearly two orders of magnitude despite sharing an identical native fold and hence contact order. We break down the determinants of this behavior and demonstra...

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Main Authors: Jelinska, Clare, Davis, Peter J., Kenig, Manca, Žerovnik, Eva, Kokalj, Saša Jenko, Gunčar, Gregor, Turk, Dušan, Turk, Vito, Clarke, David T., Waltho, Jonathan P., Staniforth, Rosemary A.
格式: Artigo
語言:Inglês
出版: The Biophysical Society 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149235/
https://ncbi.nlm.nih.gov/pubmed/21539796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.03.024
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