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Abrogation of CD30 and OX40 signals prevents autoimmune disease in FoxP3-deficient mice

Our previous studies have implicated signaling through the tumor necrosis family receptors OX40 and CD30 as critical for maintaining CD4 memory responses. We show that signals through both molecules are also required for CD4 effector-mediated autoimmune tissue damage. Under normal circumstances, mal...

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Detalhes bibliográficos
Main Authors: M.Gaspal, Fabrina, Withers, David, Saini, Manoj, Bekiaris, Vasileios, McConnell, Fiona M., White, Andrea, Khan, Mahmood, Yagita, Hideo, Walker, Lucy S.K., Anderson, Graham, Lane, Peter J.L.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149223/
https://ncbi.nlm.nih.gov/pubmed/21788408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20101484
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