IFN-γ– and IL-10–expressing virus epitope-specific Foxp3(+) T reg cells in the central nervous system during encephalomyelitis

Foxp3(+) CD4 regulatory T cells (T reg cells) are important in limiting immunopathology in infections. However, identifying pathogen-specific epitopes targeted by these cells has been elusive. Using MHC class II/peptide tetramers and intracellular cytokine staining, we identify T reg cells recognizi...

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Detalhes bibliográficos
Main Authors: Zhao, Jingxian, Zhao, Jincun, Fett, Craig, Trandem, Kathryn, Fleming, Erica, Perlman, Stanley
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2011
Assuntos:
Brief Definitive Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149215/
https://ncbi.nlm.nih.gov/pubmed/21746812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20110236
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