A Cyp2a polymorphism predicts susceptibility to NNK-induced lung tumorigenesis in mice

Lung tumors from smokers as well as lung tumors from mice exposed to tobacco carcinogens such as 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), often carry mutations in K-ras, which activates downstream-signaling pathways such as PI3K/AKT/mTOR pathway. Mice with genetic deletion of one of thr...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Hollander, M.Christine, Zhou, Xin, Maier, Colleen R., Patterson, Andrew D., Ding, Xinxin, Dennis, Phillip A.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2011
Assuntos:
Carcinogenesis
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149208/
https://ncbi.nlm.nih.gov/pubmed/21625009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgr097
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares