Dietary 5-Demethylnobiletin Inhibits Cigarette Carcinogen NNK-Induced Lung Tumorigenesis in Mice

5-Demethylnobiletin (5DN) is a unique citrus flavonoid with various beneficial bioactivities. In this study, we determined the inhibitory effects of 5DN and its two major metabolites in the 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)-induced lung tumorigenesis mouse model as well as in huma...

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Detalhes bibliográficos
Publicado no:Food Funct
Main Authors: Song, Mingyue, Wu, Xian, Charoensinphon, Noppawat, Wang, Minqi, Zheng, Jinkai, Gao, Zili, Xu, Fei, Li, Zhengze, Li, Fang, Zhou, Jiazhi, Xiao, Hang
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6375511/
https://ncbi.nlm.nih.gov/pubmed/28154877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6fo01367h
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