IGF1-R signals through the RON receptor to mediate pancreatic cancer cell migration

The RON receptor tyrosine kinase (RTK) is overexpressed in the majority of pancreatic cancers, yet its role in pancreatic cancer cell biology remains to be clarified. Recent work in childhood sarcoma identified RON as a mediator of resistance to insulin-like growth factor receptor (IGF1-R)-directed...

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Autors principals: Jaquish, Dawn V., Yu, Peter T., Shields, David J., French, Randall P., Maruyama, Karly P., Niessen, Sherry, Hoover, Heather, A.Cheresh, David, Cravatt, Ben, Lowy, Andrew M.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2011
Matèries:
Cancer Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149203/
https://ncbi.nlm.nih.gov/pubmed/21565828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgr086
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