A DNA Microarray-based Analysis of the Host Response to a Nonviral Gene Carrier: A Strategy for Improving the Immune Response

The purpose of this study was to investigate the host response to systemically administered lipid nanoparticles (NPs) encapsulating plasmid DNA (pDNA) in the spleen using a DNA microarray. As a model for NPs, we used a multifunctional envelope-type nano device (MEND). Microarray analysis revealed th...

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Bibliografski detalji
Glavni autori: Hatakeyama, Hiroto, Ito, Erika, Yamamoto, Momoko, Akita, Hidetaka, Hayashi, Yasuhiro, Kajimoto, Kazuaki, Kaji, Noritada, Baba, Yoshinobu, Harashima, Hideyoshi
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2011
Teme:
Original Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149170/
https://ncbi.nlm.nih.gov/pubmed/21386823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.24
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