Pretreatment of Hepatocyte Growth Factor Gene Transfer Mediated by Octaarginine Peptide-Modified Nanoparticles Ameliorates LPS/D-Galactosamine-Induced Hepatitis

We previously reported that an octaarginine- and pH-sensitive fusogenic peptide-modified multifunctional envelope-type nano device (R8-GALA-MEND) produces a high level of gene expression in the liver. In this study, we report on an examination of whether this gene delivery system exerts potent hepat...

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Autori principali: Hayashi, Yasuhiro, Mizuno, Ryoichi, Ikramy, Khalil A., Akita, Hidetaka, Harashima, Hideyoshi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mary Ann Liebert, Inc. 2012
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Brief Communication
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464404/
https://ncbi.nlm.nih.gov/pubmed/22963044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/nat.2012.0352
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