Effect of the Compaction and the Size of DNA on the Nuclear Transfer Efficiency after Microinjection in Synchronized Cells

The nuclear transfer process is one of the critical rate-limiting processes in transgene expression. In the present study, we report on the effect of compaction and the size of the DNA molecule on nuclear transfer efficiency by microinjection. A DNA/protamine complex- or variously-sized naked DNA mo...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Pharmaceutics
Asıl Yazarlar: Akita, Hidetaka, Kurihara, Dai, Schmeer, Marco, Schleef, Martin, Harashima, Hideyoshi
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2015
Konular:
Communication
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4491651/
https://ncbi.nlm.nih.gov/pubmed/26066769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics7020064
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