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VIP blockade leads to microcephaly in mice via disruption of Mcph1-Chk1 signaling
Autosomal recessive primary microcephaly (MCPH) is a genetic disorder that causes a reduction of cortical outgrowth without severe interference with cortical patterning. It is associated with mutations in a number of genes encoding protein involved in mitotic spindle formation and centrosomal activi...
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| Asıl Yazarlar: | , , , , , , , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society for Clinical Investigation
2011
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3148726/ https://ncbi.nlm.nih.gov/pubmed/21737879 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI43824 |
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