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Nilotinib Attenuates Renal Injury and Prolongs Survival in Chronic Kidney Disease

The tyrosine kinase inhibitor imatinib is beneficial in experimental renal diseases, but the effect of the new tyrosine kinase inhibitor nilotinib on the progression of renal failure is unknown. We administered either nilotinib or vehicle to Sprague–Dawley rats beginning 2 weeks after 5/6 nephrectom...

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Detalhes bibliográficos
Main Authors: Iyoda, Masayuki, Shibata, Takanori, Hirai, Yuki, Kuno, Yoshihiro, Akizawa, Tadao
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3148703/
https://ncbi.nlm.nih.gov/pubmed/21617123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2010111158
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