Hospitalization for pain in patients with sickle cell disease treated with sildenafil for elevated TRV and low exercise capacity

In adults with sickle cell disease (SCD), an increased tricuspid regurgitation velocity (TRV) by Doppler echocardiography is associated with increased morbidity and mortality. Although sildenafil has been shown to improve exercise capacity in patients with pulmonary arterial hypertension, it has not...

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Detalhes bibliográficos
Main Authors: Machado, Roberto F., Barst, Robyn J., Yovetich, Nancy A., Hassell, Kathryn L., Kato, Gregory J., Gordeuk, Victor R., Gibbs, J. Simon R., Little, Jane A., Schraufnagel, Dean E., Krishnamurti, Lakshmanan, Girgis, Reda E., Morris, Claudia R., Rosenzweig, Erika B., Badesch, David B., Lanzkron, Sophie, Onyekwere, Onyinye, Castro, Oswaldo L., Sachdev, Vandana, Waclawiw, Myron A., Woolson, Rob, Goldsmith, Jonathan C., Gladwin, Mark T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2011
Assuntos:
Clinical Trials and Observations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3148167/
https://ncbi.nlm.nih.gov/pubmed/21527519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-09-306167
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