A lipid-droplet-targeted O-GlcNAcase isoform is a key regulator of the proteasome

Protein-O-linked N-Acetyl-β-D-glucosaminidase (O-GlcNAcase, OGA; also known as hexosaminidase C) participates in a nutrient-sensing, hexosamine signaling pathway by removing O-linked N-acetylglucosamine (O-GlcNAc) from key target proteins. Perturbations in O-GlcNAc signaling have been linked to Alzh...

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Detaylı Bibliyografya
Asıl Yazarlar: Keembiyehetty, Chithra N., Krzeslak, Anna, Love, Dona C., Hanover, John A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Company of Biologists 2011
Konular:
Research Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3148132/
https://ncbi.nlm.nih.gov/pubmed/21807949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.083287
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