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Polymorphism in Human APOBEC3H Affects a Phenotype Dominant for Subcellular Localization and Antiviral Activity

The APOBEC3 family of cytidine deaminases is part of the innate host defense targeted toward retroviruses and retroelements. APOBEC3H is the most distantly related member of the family and carries functional polymorphisms in current human populations. Haplotype II of APOBEC3H, which is more commonly...

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Bibliografiske detaljer
Main Authors: Li, Melody M. H., Emerman, Michael
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3147987/
https://ncbi.nlm.nih.gov/pubmed/21653666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00624-11
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