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Polymorphism in Human APOBEC3H Affects a Phenotype Dominant for Subcellular Localization and Antiviral Activity

The APOBEC3 family of cytidine deaminases is part of the innate host defense targeted toward retroviruses and retroelements. APOBEC3H is the most distantly related member of the family and carries functional polymorphisms in current human populations. Haplotype II of APOBEC3H, which is more commonly...

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Autori principali: Li, Melody M. H., Emerman, Michael
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3147987/
https://ncbi.nlm.nih.gov/pubmed/21653666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00624-11
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