A Single Amino Acid in Nonstructural Protein NS4B Confers Virulence to Dengue Virus in AG129 Mice through Enhancement of Viral RNA Synthesis

Dengue (DEN) is a mosquito-borne viral disease that has become an increasing economic and health burden for the tropical and subtropical world. The lack of an appropriate animal model of DEN has greatly impeded the study of its pathogenesis and the development of vaccines/antivirals. We recently rep...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Grant, Dixon, Tan, Grace K., Qing, Min, Ng, Jowin K. W., Yip, Andy, Zou, Gang, Xie, Xuping, Yuan, Zhiming, Schreiber, Mark J., Schul, Wouter, Shi, Pei-Yong, Alonso, Sylvie
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2011
Soggetti:
Pathogenesis and Immunity
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3147917/
https://ncbi.nlm.nih.gov/pubmed/21632767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00665-11
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi