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The Lysyl Oxidase Propeptide Interacts with the Receptor-Type Protein Tyrosine Phosphatase Kappa and Inhibits β-Catenin Transcriptional Activity in Lung Cancer Cells

The propeptide region of the lysyl oxidase proenzyme (LOX-PP) has been shown to inhibit Ras signaling in NIH 3T3 and lung cancer cells with activated RAS, but its mechanism of action is poorly understood. Here, a yeast two-hybrid assay of LOX-PP-interacting proteins identified a clone encoding the i...

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מידע ביבליוגרפי
Main Authors: Sánchez-Morgan, Nuria, Kirsch, Kathrin H., Trackman, Philip C., Sonenshein, Gail E.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology 2011
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3147807/
https://ncbi.nlm.nih.gov/pubmed/21690299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01426-10
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