Impact of the E540V Amino Acid Substitution in GyrB of Mycobacterium tuberculosis on Quinolone Resistance

Amino acid substitutions conferring resistance to quinolones in Mycobacterium tuberculosis have generally been found within the quinolone resistance-determining regions (QRDRs) in the A subunit of DNA gyrase (GyrA) rather than the B subunit of DNA gyrase (GyrB). To clarify the contribution of an ami...

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Tallennettuna:
Bibliografiset tiedot
Päätekijät: Kim, Hyun, Nakajima, Chie, Yokoyama, Kazumasa, Rahim, Zeaur, Kim, Youn Uck, Oguri, Hiroki, Suzuki, Yasuhiko
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2011
Aiheet:
Mechanisms of Resistance
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3147658/
https://ncbi.nlm.nih.gov/pubmed/21646485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00042-11
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