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Requirement for Invariant Chain in Macrophages for Mycobacterium tuberculosis Replication and CD1d Antigen Presentation

Mycobacterium tuberculosis is an intracellular bacterium that persists in phagosomes of myeloid cells. M. tuberculosis-encoded factors support pathogen survival and reduce fusion of phagosomes with bactericidal lysosomal compartments. It is, however, not entirely understood if host factors that medi...

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Bibliographic Details
Main Authors: Sillé, Fenna C. M., Martin, Constance, Jayaraman, Pushpa, Rothchild, Alissa, Fortune, Sarah, Besra, Gurdyal S., Behar, Samuel M., Boes, Marianne
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3147586/
https://ncbi.nlm.nih.gov/pubmed/21576321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01108-10
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