Expression of the Type 1 Pneumococcal Pilus Is Bistable and Negatively Regulated by the Structural Component RrgA

The pneumococcal type 1 pilus, which is present in 25 to 30% of clinical isolates, has been associated with increased adherence and inflammatory responses and is being evaluated as a potential vaccine candidate. Here we show that expression of the pilus is bistable as a result of the molecular inter...

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Bibliografiske detaljer
Main Authors: Basset, Alan, Turner, Keith H., Boush, Elizabeth, Sayeed, Sabina, Dove, Simon L., Malley, Richard
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2011
Fag:
Molecular Pathogenesis
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3147576/
https://ncbi.nlm.nih.gov/pubmed/21576325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.05117-11
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