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Dual Function Inhibitors of Relevance to Chronic Obstructive Pulmonary Disease
The general strategy and rationale underlying the design of COPD therapeutics that possess protease inhibitory activity and are also capable of releasing a species that attenuates inflammation by inhibiting caspase-1, are described. The synthesis and in vitro biochemical evaluation of a dual functio...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2010
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3147253/ https://ncbi.nlm.nih.gov/pubmed/21511470 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2010.12.033 |
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