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A high-throughput protocol for mutation scanning of the BRCA1 and BRCA2 genes
BACKGROUND: Detection of mutations by DNA sequencing can be facilitated by scanning methods to identify amplicons which may have mutations. Current scanning methods used for the detection of germline sequence variants are laborious as they require post-PCR manipulation. High resolution melting (HRM)...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3146935/ https://ncbi.nlm.nih.gov/pubmed/21702907 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-11-265 |
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