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Granulocyte colony stimulating factor attenuates inflammation in a mouse model of amyotrophic lateral sclerosis

BACKGROUND: Granulocyte colony stimulating factor (GCSF) is protective in animal models of various neurodegenerative diseases. We investigated whether pegfilgrastim, GCSF with sustained action, is protective in a mouse model of amyotrophic lateral sclerosis (ALS). ALS is a fatal neurodegenerative di...

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Bibliografiske detaljer
Main Authors: Pollari, Eveliina, Savchenko, Ekaterina, Jaronen, Merja, Kanninen, Katja, Malm, Tarja, Wojciechowski, Sara, Ahtoniemi, Toni, Goldsteins, Gundars, Giniatullina, Raisa, Giniatullin, Rashid, Koistinaho, Jari, Magga, Johanna
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2011
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3146845/
https://ncbi.nlm.nih.gov/pubmed/21711557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-8-74
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