High Chromosome Number in hematological cancer cell lines is a Negative Predictor of Response to the inhibition of Aurora B and C by GSK1070916

BACKGROUND: Aurora kinases play critical roles in mitosis and are being evaluated as therapeutic targets in cancer. GSK1070916 is a potent, selective, ATP competitive inhibitor of Aurora kinase B and C. Translation of predictive biomarkers to the clinic can benefit patients by identifying the tumors...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Moy, Christopher, Oleykowski, Catherine A, Plant, Ramona, Greshock, Joel, Jing, Junping, Bachman, Kurtis, Hardwicke, Mary Ann, Wooster, Richard, Degenhardt, Yan
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2011
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3146841/
https://ncbi.nlm.nih.gov/pubmed/21762492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-9-110
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars