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Analysis of glutamine dependency in non-small cell lung cancer: GLS1 splice variant GAC is essential for cancer cell growth

One of the hallmarks of cancer is metabolic deregulation. Many tumors display increased glucose uptake and breakdown through the process of aerobic glycolysis, also known as the Warburg effect. Less studied in cancer development and progression is the importance of the glutamine (Gln) pathway, which...

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Autori principali: van den Heuvel, A. Pieter J., Jing, Junping, Wooster, Richard F., Bachman, Kurtis E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3469476/
https://ncbi.nlm.nih.gov/pubmed/22892846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.21348
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