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Analysis of glutamine dependency in non-small cell lung cancer: GLS1 splice variant GAC is essential for cancer cell growth

One of the hallmarks of cancer is metabolic deregulation. Many tumors display increased glucose uptake and breakdown through the process of aerobic glycolysis, also known as the Warburg effect. Less studied in cancer development and progression is the importance of the glutamine (Gln) pathway, which...

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Bibliografische gegevens
Hoofdauteurs: van den Heuvel, A. Pieter J., Jing, Junping, Wooster, Richard F., Bachman, Kurtis E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Landes Bioscience 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3469476/
https://ncbi.nlm.nih.gov/pubmed/22892846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.21348
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