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Steroidogenic Enzymes and Stem Cell Markers Are Upregulated during Androgen Deprivation in Prostate Cancer

Considerable levels of testosterone and dihydrotestosterone (DHT) are found in prostate cancer (PCa) tissue after androgen deprivation therapy. Treatment of surviving cancer-initiating cells and the ability to metabolize steroids from precursors may be the keystones for the appearance of recurrent t...

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Detalles Bibliográficos
Autores principales: Pfeiffer, Minja J, Smit, Frank P, Sedelaar, John PM, Schalken, Jack A
Formato: Artigo
Lenguaje:Inglês
Publicado: ScholarOne 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3146625/
https://ncbi.nlm.nih.gov/pubmed/21365123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2010.00143
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