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Steroidogenic Enzymes and Stem Cell Markers Are Upregulated during Androgen Deprivation in Prostate Cancer

Considerable levels of testosterone and dihydrotestosterone (DHT) are found in prostate cancer (PCa) tissue after androgen deprivation therapy. Treatment of surviving cancer-initiating cells and the ability to metabolize steroids from precursors may be the keystones for the appearance of recurrent t...

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Detalhes bibliográficos
Main Authors: Pfeiffer, Minja J, Smit, Frank P, Sedelaar, John PM, Schalken, Jack A
Formato: Artigo
Idioma:Inglês
Publicado em: ScholarOne 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3146625/
https://ncbi.nlm.nih.gov/pubmed/21365123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2010.00143
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