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Costimulation and T cells as therapeutic targets
Full activation and differentiation of resting T cells into effector T cells requires at least two signals, the first through engagement of the T cell antigen receptor (TCR) by the antigen-MHC complex on antigen presenting cells (APC), and the second by engagement of co-stimulatory molecules such as...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3146352/ https://ncbi.nlm.nih.gov/pubmed/20732645 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.berh.2009.12.015 |
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