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Costimulation and T cells as therapeutic targets

Full activation and differentiation of resting T cells into effector T cells requires at least two signals, the first through engagement of the T cell antigen receptor (TCR) by the antigen-MHC complex on antigen presenting cells (APC), and the second by engagement of co-stimulatory molecules such as...

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Autors principals: Gizinski, Alison M., Fox, David A., Sarkar, Sujata
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3146352/
https://ncbi.nlm.nih.gov/pubmed/20732645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.berh.2009.12.015
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