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Association of Mouse Dlg4 (PSD-95) Gene Deletion and Human DLG4 Gene Variation With Phenotypes Relevant to Autism Spectrum Disorders and Williams’ Syndrome

OBJECTIVE: Research is increasingly linking autism spectrum disorders and other neurodevelopmental disorders to synaptic abnormalities (“synaptopathies”). PSD-95 (postsynaptic density-95, DLG4) orchestrates protein-protein interactions at excitatory synapses and is a major functional bridge intercon...

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Detalhes bibliográficos
Main Authors: Feyder, Michael, Karlsson, Rose-Marie, Mathur, Poonam, Lyman, Matthew, Bock, Roland, Momenan, Reza, Munasinghe, Jeeva, Scattoni, Maria Luisa, Ihne, Jessica, Camp, Marguerite, Graybeal, Carolyn, Strathdee, Douglas, Begg, Alison, Alvarez, Veronica A., Kirsch, Peter, Rietschel, Marcella, Cichon, Sven, Walter, Henrik, Meyer-Lindenberg, Andreas, Grant, Seth G.N., Holmes, Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3146008/
https://ncbi.nlm.nih.gov/pubmed/20952458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1176/appi.ajp.2010.10040484
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