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Tolerance to ethanol intoxication after chronic ethanol: role of GluN2A and PSD-95

The neural and genetic factors underlying chronic tolerance to alcohol are currently unclear. The GluN2A NMDAR subunit and the NMDAR-anchoring protein PSD-95 mediate acute alcohol intoxication and represent putative mechanisms mediating tolerance. We found chronic intermittent ethanol exposure (CIE)...

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Detalhes bibliográficos
Main Authors: Daut, Rachel Anne, Busch, Erica Faye, Ihne, Jessica, Fisher, Daniel, Mishina, Masayoshi, Grant, Seth, Camp, Marguerite, Holmes, Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4085154/
https://ncbi.nlm.nih.gov/pubmed/24397780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/adb.12110
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