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OCT4 Expression Enhances Features of Cancer Stem Cells in a Mouse Model of Breast Cancer

The cancer stem cell (CSC) hypothesis proposes that CSCs are responsible for metastasis and disease recurrence. Therefore, targeting CSCs has the potential to significantly improve outcomes for cancer patients. The OCT4 transcription factor gene is a master gene that plays a key role in the self-ren...

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Detalhes bibliográficos
Main Authors: Kim, Ran-Ju, Nam, Jeong-Seok
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Association for Laboratory Animal Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3145994/
https://ncbi.nlm.nih.gov/pubmed/21826175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5625/lar.2011.27.2.147
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