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Parameterization of Org27569: An Allosteric Modulator of the Cannabinoid CB(1) G-Protein Coupled Receptor

The cannabinoid CB(1) receptor is a Class A G-protein coupled receptor (GPCR) that is the most widely expressed GPCR in the brain. Many GPCRs contain allosteric binding sites for endogenous and/or synthetic ligands, which are topographically distinct from the agonist-binding site, which is known as...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Iliff, Hadley A., Lynch, Diane L., Kotsikorou, Evangelia, Reggio, Patricia H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3145811/
https://ncbi.nlm.nih.gov/pubmed/21523790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcc.21794
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