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Effects of the cannabinoid CB(1) receptor allosteric modulator ORG 27569 on reinstatement of cocaine- and methamphetamine-seeking behavior in rats

BACKGROUND: Cannabinoid CB(1) receptors play an essential role in drug addiction. Given the side effect profiles of orthosteric CB(1) antagonism, new strategies have been attempted to modulate this target, such as CB(1) receptor allosteric modulation. However, the effect of CB(1) allosteric modulati...

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Autori principali: Jing, Li, Qiu, Yanyan, Zhang, Yanan, Li, Jun-Xu
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4161648/
https://ncbi.nlm.nih.gov/pubmed/25169627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drugalcdep.2014.08.004
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