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Eos Negatively Regulates Human γ-globin Gene Transcription during Erythroid Differentiation

BACKGROUND: Human globin gene expression is precisely regulated by a complicated network of transcription factors and chromatin modifying activities during development and erythropoiesis. Eos (Ikaros family zinc finger 4, IKZF4), a member of the zinc finger transcription factor Ikaros family, plays...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Yu, Hai-Chuan, Zhao, Hua-Lu, Wu, Zhi-Kui, Zhang, Jun-Wu
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3145782/
https://ncbi.nlm.nih.gov/pubmed/21829552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0022907
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