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Cardiomyocyte Specific Ablation of p53 Is Not Sufficient to Block Doxorubicin Induced Cardiac Fibrosis and Associated Cytoskeletal Changes

Doxorubicin (Dox) is an anthracycline used to effectively treat several forms of cancer. Unfortunately, the use of Dox is limited due to its association with cardiovascular complications which are manifested as acute and chronic cardiotoxicity. The pathophysiological mechanism of Dox induced cardiot...

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Detalhes bibliográficos
Main Authors: Feridooni, Tiam, Hotchkiss, Adam, Remley-Carr, Sarah, Saga, Yumiko, Pasumarthi, Kishore B. S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3145765/
https://ncbi.nlm.nih.gov/pubmed/21829519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0022801
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