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Active immunization using a single dose immunotherapeutic abates established EAE via IL-10 and regulatory T cells
Stimulation of Ag-specific inducible Treg can enhance resolution of autoimmune disease. Conventional methods to induce Treg often require induction of autoimmune disease or subjection to infection. Reovirus adhesin, protein σ1 (pσ1), can successfully facilitate tolerance when fused to a tolerogen. W...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3145764/ https://ncbi.nlm.nih.gov/pubmed/21268002 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201041104 |
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